Weiguo Cui

Credentials: PhD

Position title: Senior Investigator

Email: weiguo.cui@bcw.edu

I have been studying the role of T-cell response (TCR) and cytokine signaling in autoreactive CD8 T cells in NOD mouse models. Our research approach involves murine transgenic models, single cell RNA and TCR sequencing. Our collaborative work with Drs. Yi-Guang Chen and John Corbett has demonstrated the cytokine signaling downstream of IL-21 and Il-27 affects CD8 T cell from progenitor to effector transition, which is indispensable for the pathogenesis of diabetes.